Developmental regulation of the chicken βB1-crystallin promoter in transgenic mice
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چکیده
منابع مشابه
Developmental regulation of the chicken βB1-crystallin promoter in transgenic mice
The cis-elements responsible for the high-level, lens-specific expression of the chicken beta B1-crystallin gene were investigated by generating mice harboring beta B1-crystallin promoter/chloramphenicol acetyl transferase (CAT) transgenes. Deletion of promoter sequences -434/-153 and -152/-127 as well as site-directed mutagenesis of the PL1 (-116/-102) and Pl2 (-90/-76) elements significantly ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 1996
ISSN: 0925-4773
DOI: 10.1016/0925-4773(96)00533-3